Following the evidence

102 results

• In the newsSeptember 16, 2026ScienceDaily

  Scientists find a natural gut compound that helps heal the intestine

  A compound made by gut bacteria from foods such as walnuts and berries may help repair the intestinal lining, per the source.
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• In the journalsSeptember 13, 2026Orthopaedic surgery

  The Effect of Extracorporeal Shockwave Therapy in Tendinopathy: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials

  Guo NY, Wang SQ, Liu W, Mao ZM, Wang JQ, Xu BB.
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• In the newsSeptember 13, 2026ScienceDaily

  Nearly 10,000 patients reveal what works best for knee arthritis pain relief

  An analysis across trials ranks knee braces, water-based therapy and regular exercise highest for pain and function, per the source.
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• In the newsSeptember 6, 2026ScienceDaily

  Scientists discover a hidden immune signal that helps spinal cords regrow

  In zebrafish, researchers find an immune signal that lets injured spinal cord fibres grow again, per the source.
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• In the newsSeptember 3, 2026Cosmetics Business

  Same INCI, different origins: Why PDRN sourcing matters

  A trade piece on why two ingredients with the same label name can differ by where the PDRN comes from, per the source.
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• In the journalsSeptember 1, 2026Journal of drugs in dermatology : JDD

  Real-World Cases Using Phyto Polydeoxyribonucleotide (PDRN) Serum

  Wu Y, Guénin S, Fung E, Brieva P, Li X, Lin LC, Raya CM, Rocha M, Sayed K, Schlesinger T, Sullivan J, Waibel J
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• In the journalsAugust 31, 2026Purinergic signalling

  Interaction between purinergic signalling and purinergic modulators with skin wound repair effectors: a systematic review of preclinical in vivo models

  Pelinsari SM, Goncalves RV, da Silva Mattosinhos P, Sarandy MM, Vilela EF, Novaes RD.
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• In the journalsAugust 28, 2026Frontiers in medicine

  Case Report: Ultrasound-guided hydrodissection targeting the subsynovial connective tissue with dynamic ultrasound assessment in refractory carpal tunnel syndrome: a report of two cases

  Lee D, Ahn T, Oh M, Lee J, Woo H, Kwon H, Park C, Kim CH, Ahn JY, Moon J, Lim DW.
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• In the newsAugust 28, 2026ScienceDaily

  Scientists discover why damaged nerves struggle to heal

  A study in mice finds a protein that holds back the regrowth of injured nerve fibres, per the source.
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• In the journalsAugust 18, 2026Colloids and surfaces. B, Biointerfaces

  Multifunctional therapeutic platform based on polydeoxyribonucleotide-loaded calcium carbonate particles for osteoarthritis management

  Jung SY, Kim HJ, Kim SE, Park K.
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• In the journalsAugust 16, 2026International journal of molecular sciences

  The Role of Polydeoxyribonucleotide as a Biotherapy for Musculoskeletal Disorders

  Choi J, Yoo YM.
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• In the journalsAugust 11, 2026International journal of biological macromolecules

  Surfactant-tailored alginate/pectin hydrogel beads delivering polydeoxyribonucleotide for inflammatory symptom alleviation and gut microbiota regulation

  Zou Y, Liu X, Ding B, Chen Y, Qu W, Liu K, Zhang R, Yuan Y, Liu H, Dai W, Zhang H, Liu Q, Ren C.
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• In the journalsAugust 1, 2026Inflammatory bowel diseases

  Effect of polydeoxyribonucleotide as a potential therapeutic agent to enhance the healing of Crohn's perianal fistula

  Kim HK, Yoon YS, Lee JL, Park EJ, Kim MH, Kim YI, Kim CW, Park IJ, Lim SB, Yu CS.
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• In the journalsJuly 28, 2026JPRAS open

  Beyond the needle: psychosocial and quality-of-life outcomes following facial aesthetic injectable treatments

  Michon A.
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• In the journalsJuly 28, 2026Biomaterials science

  Mechanical stress-driven conformational compaction of polydeoxyribonucleotide for enhanced transdermal regenerative therapy

  Jeon S, Lee JI, Shim SB, Kim CH, Oh TJ, Gonçalves M, Kim JW.
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• In the journalsJuly 18, 2026Journal of functional biomaterials

  Plant-Derived Polynucleotides/Polydeoxyribonucleotides in Skin Biomaterials: Delivery Platforms and Bioactivity Attribution

  Kim HJ, Lee JW, Kim S, Son KH.
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• In the newsJuly 16, 2026BeautyMatter

  Vegan PDRN Is Reshaping Regenerative Skincare as Biotech Alternatives Gain Momentum

  A trade report on PDRN made without animal sources, from fermentation, microalgae and plants, and why demand for it is growing, per the source.
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• In the journalsJuly 10, 2026Cureus

  Polynucleotides and Polydeoxyribonucleotides for Skin Rejuvenation, Postoperative Scar Prevention, and Wound Healing: A Systematic Review of Randomized Clinical Trials

  Alhussain AM, Turki M Albusayys S, Alfhadi MA, Bu Mozah SA, AlShammari SSS, Alanazi HAM, Adil Alqazanli S, Nou
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• In the journalsJuly 10, 2026PloS one

  Topical medium-length PDRN enhances dermal extracellular matrix repair in photodamaged skin via PI3K-Akt/TGF-β-regulated pathways

  Ye R, Wang Q, Du L, Li L, Hu F.
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• In the journalsJuly 9, 2026Scientific Reports

  Characterization of microbiome diversity and its association with healing outcomes in diabetic foot ulcer patients

  How the wound microbiome relates to whether a diabetic foot ulcer heals. Not a PDRN paper; listed for the system.
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• In the journalsJuly 8, 2026Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology

  One-day rejuvenation: a preliminary case series of a multimodal protocol combining Q-switched 1064 nm laser, botulinum toxin, and laser-assisted delivery of PDRN and retinoids

  Rodrigo Crisanto de Oliveira R.
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• In the journalsJune 26, 2026Journal of clinical medicine

  Hyaluronic Acid Fillers Versus Polynucleotides for Under-Eye Rejuvenation

  Khan RS, Hafeez K.
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• In the journalsJune 24, 2026Frontiers in medicine

  Comparative evaluation of short vs. long needles in deep ultrasound-guided pharmacopuncture for acute low back pain: study protocol

  Kim K, Lee YU, Kwon R, Chu H, Park S, Hong HJ, Lee Y, Kwon J, Song J, Kwon S, Leem J, Kim CH.
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• In the newsJune 19, 2026ScienceDaily

  One injection reversed osteoarthritis in weeks

  A Colorado team reports that a single injection restored arthritic joints in animal studies; human trials are expected, per the source.
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• In the newsJune 16, 2026ScienceDaily

  New procedure delivers lasting knee arthritis pain relief without surgery

  A minimally invasive treatment that blocks inflammation-driving blood vessels in the knee gave relief lasting at least a year, per the source.
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• In the journalsJune 15, 2026Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]

  Global Trends and Evidence Evaluation: A Systematic Review of Polynucleotide and Polydeoxyribonucleotide Therapy in Dermatology

  Kream EJ, Anooshiravani N, Hosking AM, Boen M, Fabi SG.
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• In the newsJune 12, 2026ScienceDaily

  Stanford scientists regrow lost cartilage and reverse arthritis in major breakthrough

  Blocking an ageing-related protein restored cartilage in old mice, with similar signs in human cartilage samples, per the source.
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• In the journalsJune 11, 2026Transplantation proceedings

  The Therapeutic Effect of Polydeoxyribonucleotide on Lung Ischemia-Reperfusion Injury

  Sun F, Xu C.
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• In the journalsJune 10, 2026Experimental and Molecular Medicine

  Next-generation therapies for osteoarthritis: the evolving role of cell therapy products

  A review of cell-based therapies for osteoarthritis and the trials ahead of them. Not a PDRN paper; listed for the system.
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• In the journalsJune 6, 2026Talanta

  SEC-MALS analysis of polydeoxyribonucleotides: Revealing product heterogeneity and enabling measurement standardization

  Zhou B, Feng N, Nong X, Chen S, Li J, Zeng Z, Zhang W, Zhai X, Li L, Mi W, Hu Z.
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• In the journalsMay 29, 2026Biomedicines

  Polydeoxyribonucleotide Mitigates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice Through the PKA/CREB/NF-κB Signaling Pathway

  Lee S, Hwang L, Kim SH, Lee SH, Han JH, Jeon JW, Shin HC, Ko IG.
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• In the journalsMay 29, 2026International journal of molecular sciences

  Comparative ESEM Characterization and Collagen-Related Tissue Responses to Commercial Injectable Bioregenerative Formulations in a Murine Model

  Marcondes APSD, Barcellos FVC, Lacerda MRP, Costa ALO, Queiroz LDRP, Oliveira JR, Milo BG, da Costa TBCR, Sant
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• In the journalsMay 23, 2026npj Biofilms and Microbiomes

  Ulcerative colitis-driven gut dysbiosis exacerbates periodontal bone loss through the gut-oral axis

  How gut inflammation in colitis worsens gum disease, in a mouse model. Not a PDRN paper; listed for the system.
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• In the newsMay 23, 2026ScienceDaily

  Scientists “recharge” damaged nerves to ease chronic pain

  Work in human tissue and mice tests whether restoring mitochondria in damaged nerve cells eases nerve pain, per the source.
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• In the newsMay 22, 2026ScienceDaily

  Scientists discover simple way to relieve arthritis pain without pills or surgery

  In a year-long trial, changing the angle of the foot while walking reduced knee pain as much as common medication, per the source.
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• In the newsMay 20, 2026ScienceDaily

  MIT scientists discover amino acid that helps the gut heal itself

  In mice, a diet rich in one amino acid helped stem cells rebuild damaged intestinal tissue, per the source.
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• In the newsMay 19, 2026ScienceDaily

  Breakthrough drug reverses aging in skin and dramatically speeds healing

  A study in mice reports that clearing aged cells from skin speeds the closing of wounds, per the source.
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• In the journalsMay 15, 2026Cureus

  Polydeoxyribonucleotide (PDRN) in Post-procedure Recovery in Aesthetic Medicine: A Narrative Review

  Flores Rodríguez JC, Toledo Avelar LE, Yi K, Merino Arellano R, Porras Zamora BM, Martínez LV.
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• In the journalsMay 14, 2026International journal of molecular sciences

  Synergistic Regenerative Strategies: Combining Polydeoxyribonucleotide with Biochemical and Physical Agents

  Choi J, Jang SK, Lee D, Yoo YM.
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• In the journalsApril 22, 2026Aesthetic surgery journal. Open forum

  Comparative Effects of Injectable Biostimulatory Agents (Calcium Hydroxyapatite, New Cellular Treatment Factor, VAMP, and Human Exosomes) and Their Combination on Skin Regeneration

  Adel N, Kolenda J, Hernández Gómez Crespo F, Zavala Resendiz GY, Jo YK, Thulesen IV, Saucillo JR.
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• In the newsApril 13, 2026Harvard Health

  Study questions the value of wrist splinting for carpal tunnel syndrome

  A randomised trial found rigid splints and soft bandages gave similarly small improvements over 12 weeks, per the source.
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• In the journalsApril 9, 2026Journal of orthopaedic surgery and research

  Polydeoxyribonucleotide improves scar healing following limited scar resection for chronic Achilles tendon rupture in a rat model

  Zhang H, Wu W, Su Y, Xiao C, Wang H, Cui F, Duan W, Meng X.
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• In the newsApril 9, 2026Healthline

  Is a cure for osteoarthritis on the horizon? New therapies show promise

  Three approaches funded by ARPA-H, bone and cartilage regeneration and engineered living knee implants, aim to restore joint function rather than manage pain, per the source.
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• In the newsMarch 30, 2026ScienceDaily

  Simple therapies beat drugs for knee arthritis pain relief

  A comparison of treatments for knee osteoarthritis finds non-drug therapies ahead for pain relief, per the source.
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• In the journalsMarch 26, 2026Scientific Reports

  In vitro and in vivo evaluation of oleuropein loaded hyalurosomes for diabetic foot ulcer healing

  A topical nanocarrier for diabetic wounds, tested in a rat model. Not a PDRN paper; listed for the system.
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• In the journalsMarch 19, 2026JAAD case reports

  Safety and feasibility of the ISO-LPR protocol (isotretinoin, laser, and polydeoxyribonucleotide) in severe nodulocystic acne: A case report

  Crisanto de Oliveira RR.
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• In the journalsMarch 17, 2026Biomacromolecules

  Orthogonal Molecular Weight Analysis of Challenging Macromolecules Using MALS and Mass Photometry: Example of Polydeoxyribonucleotide

  Chen S, Zhou B, Zhang W, Shang X, Nong X, Li J, Feng N, Zhai X, Jin S, Mi W, Hu Z.
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• In the journalsMarch 17, 2026BMC biotechnology

  A novel method to encapsulate polydeoxyribonucleotides extracted from trout into exosomes and applications in skin recovery

  Chang Y, Park JY, Hwang D, Kim MT, Yoon S, Cho SH.
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• In the journalsMarch 3, 2026Marine drugs

  Polydeoxyribonucleotide (PDRN) Selectively Promotes Osteoblast Differentiation Without Affecting Osteoclastogenesis

  Jeon Y, Heo E, Jin X, Lee DK, Che X, Kim HJ, Byun SH, Choi JY, Choi J, Oh J.
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• In the journalsMarch 1, 2026Marine drugs

  Hyaluronic Acid-like Skin Plumping and Radiance Benefits of a <i>Porphyridium</i> Sulfated Exopolysaccharide- and Natural PDRN-Rich Extract

  Havas F, Krispin S, Cohen M, Attia-Vigneau J.
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• In the newsFebruary 21, 2026ScienceDaily

  New oxygen gel could prevent amputation in diabetic wound patients

  Researchers describe a gel that delivers oxygen into diabetic wounds that are slow to close, per the source.
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• In the journalsFebruary 18, 2026Orthopedic reviews

  Advances in hyaluronic acid therapy for knee osteoarthritis: monotherapy and combination strategies: an evidenced based review

  Cao KX, Tang HNA, Tran MH.
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• In the journalsFebruary 17, 2026Scientific Reports

  Topical treatment of diabetic foot ulcers using a novel quercetin-loaded hyaluosome gel nanoformulation

  A quercetin gel for diabetic foot ulcers, preclinical. Not a PDRN paper; listed for the system.
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• In the journalsFebruary 10, 2026Pharmaceuticals (Basel, Switzerland)

  Guang Chenpi Extract as a Multifunctional Phytotherapeutic: Enhanced Effects with Ergothioneine and Polydeoxyribonucleotide on Redox Homeostasis and Tissue Resilience

  Cen Z, Chen Z, Wang D, Zuo Y, Peng J, Chen J, Chen X.
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• In the journalsFebruary 6, 2026Current issues in molecular biology

  Oral and Intranasal Administration of Polydeoxyribonucleotide Isolated from <i>Porphyra</i> sp. Ameliorates Acute Lung Injury via Suppressing Proinflammatory Cytokine Production in Mice

  Lee GY, Lee WS, Han J, Yoo YC.
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• In the journalsFebruary 1, 2026Journal of cosmetic dermatology

  New Cellular Treatment Factor (NCTF) and Polydeoxyribonucleotide (VAMP) Injections Enhance Skin Regeneration: Experimental and Histological Evidence

  Adel N, Kolenda J.
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• In the journalsJanuary 30, 2026Annals of plastic surgery

  An Evidence-Based Assessment of Adjuvant Therapy in Autologous Fat Transfer: Ranking of the Potential Agents

  Sarpong C, Oh I, Bouz A, Gupta S.
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• In the journalsJanuary 22, 2026Journal of functional biomaterials

  Paeonia lactiflora Callus-Derived Polynucleotides Enhance Collagen Accumulation in Human Dermal Fibroblasts

  Hwang S, Park S, Lee JW, Park M, Nguyet LA, Hwang Y, Ahn K, Shin HY, Son KH.
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• In the newsJanuary 20, 2026ScienceDaily

  Stanford scientists found a way to regrow cartilage and stop arthritis

  A treatment that blocks an ageing-related protein helped prevent arthritis after knee injuries in mice, per the source.
  →
• In the journalsJanuary 17, 2026Tissue engineering and regenerative medicine

  Polydeoxyribonucleotide (PDRN) in Dentistry: Narrative Review for Mechanisms and Emerging Clinical Applications

  Ku JK, Yun PY, Jeong YK.
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• In the journalsJanuary 12, 2026Journal of oral & facial pain and headache

  Efficacy of prolotherapy in temporomandibular joint disorders with hypertonic dextrose and Polydeoxyribonucleotide (PDRN)

  Choi JW, Kim YK, Yun PY, Ku JK.
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• In the journalsJanuary 1, 2026Macromolecular bioscience

  Nanoformulated PDRN Improves Anti-Inflammatory and Wound Healing Activities

  Kang JH, Jeon MJ, Kim SE, Hwang WK, Lee MY.
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• In the journalsJanuary 1, 2026Yonsei medical journal

  Efficacy of Submucosal Polydeoxyribonucleotide Injection after Impacted Mandibular Third Molar Extraction: A Randomized Controlled Trial

  Kim HJ, Park SY, Kwon H, Fang Y, Kwon Y, Lee C.
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• In the journalsDecember 30, 2025Scientific Reports

  Gene expression analysis of diabetic foot ulcers reveals the potential impact of Levofloxacin on wound healing

  Gene expression in diabetic foot ulcers and an antibiotic's possible effect on healing. Not a PDRN paper; listed for the system.
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• In the journalsDecember 25, 2025Plastic and aesthetic nursing

  Skin Tightening and Brightening: Vaginal Rejuvenation Using Polydioxanone (PDO) Threads and Polydeoxyribonucleotide (PDRN)

  Delgado C.
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• In the journalsDecember 24, 2025International journal of molecular sciences

  Anti-Aging Efficacy of Low-Molecular-Weight Polydeoxyribonucleotide Derived from <i>Paeonia lactiflora</i>

  Bak SU, Jung MS, Kim DJ, Jin HU, Lee SY, An CE.
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• In the journalsDecember 20, 2025International journal of biological macromolecules

  Multifunctional gelatin/phycocyanin composite hydrogel for infected wound therapy: pH-responsive drug release, antibacterial/antioxidant properties, and enhanced healing

  Du Y, Nie Y, Zhang R, Liu G, Ren C, Li W, Tang Z.
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• In the journalsDecember 8, 2025Cureus

  Beneficial Effect of Polydeoxyribonucleotide in the Treatment of Actinic Cheilitis: A Case Report

  Jara P.
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• In the journalsDecember 6, 2025Cellular and molecular biology (Noisy-le-Grand, France)

  Skin regenerative potential of polydeoxyribonucleotide isolated from Saussurea involucrata

  Kim DJ, Bak SU, Lee SY, Jung MS, Jin HU, An CE.
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• In the journalsDecember 5, 2025Clinical case reports

  Refractory Alopecia Areata of the Beard: Novel Improvement Through Exosome Therapy With Signs of Hair Repigmentation

  Shadid A, Nagshabandi KN, AlRuhaimi DK, Al-Omair A, Alsadhan A.
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• In the journalsDecember 1, 2025Journal of the Korean Association of Oral and Maxillofacial Surgeons

  Prolotherapy for temporomandibular joint disorders: an updated comprehensive review

  Kim Y, Kim MJ, Yun PY, Ku JK.
  →
• In the journalsDecember 1, 2025Journal of cosmetic dermatology

  Letter to the Editor: Use of PDRN and Nd:YAG Q-Switched 1064 nm Laser in the Management of Post-Inflammatory Hyperpigmentation Following Laser Hair Removal Complication

  de Oliveira RRC.
  →
• In the journalsNovember 24, 2025International journal of molecular sciences

  The Mitigating Effect and Mechanism of Polydeoxyribonucleotide Against Zoledronic Acid-Induced Growth Suppression of Human Gingival Fibroblasts

  Pachhapure S, Shin YM, Kim DG, Choi DR, Yun JI, Kim JH, Jang BC.
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• In the journalsNovember 23, 2025Current issues in molecular biology

  Modulating Skin Aging Molecular Targets and Longevity Drivers Through a Novel Natural Product: Rose-Derived Polydeoxyribonucleotide (Rose PDRN)

  Cavagnino A, Azadiguian G, Breton L, Baraibar M, Black AF.
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• In the journalsNovember 16, 2025Cureus

  Effect of Polynucleotides on Apex Lingual Regeneration After Amputation Due to a Car Accident: A Case Report

  Saavedra P, Walker L, Arroyo P.
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• In the newsNovember 11, 2025Tien Phong

  Trí tuệ trẻ Việt Nam tỏa sáng tại Viện Hàn lâm Khoa học Hoàng gia Anh

  A report on the first event on Vietnamese science held at the Royal Society in London, where twelve young teams presented, our founder's work on PDRN among them, per the source.
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• In the journalsNovember 10, 2025Eye & contact lens

  Effect of Polydeoxyribonucleotide-Releasing Contact Lenses on Corneal Wound Healing

  Ryu Y, Son HJ, Hwang JS, Oh SH, Lee JH, Kim GB, Shin YJ.
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• In the journalsNovember 7, 2025ACS applied bio materials

  A Multicomponent Salmon PDRN/Sodium Alginate/Gelatin Hydrogel Promotes Infected Wound Repair in Rat

  Zhao Y, Wang Y, Sheng W, Xia Q, Li X, Stoika R, Cai L, Wang L.
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• In the journalsNovember 5, 2025Clinics in orthopedic surgery

  Atelocollagen Improves Bone-to-Tendon Interface Healing in a Rabbit Model of Chronic Rotator Cuff Tear Compared with Polydeoxyribonucleotide

  Han J, Zhang ZF, Fang SY, Cui YM, Han SC.
  →
• In the journalsOctober 25, 2025Advanced materials (Deerfield Beach, Fla.)

  Mesenchymal Stem Cell-Inspired Microneedle Platform for NIR-responsive Immunomodulation and Accelerated Chronic Wound Healing

  Moon CH, Ko HG, Lee H, Bang S, Kang HS, Gwon JY, Seo JH, Lee N, Jeon SW, Kim YA, Yoon JS, Cha KY, Kang MH, Lee
  →
• In the journalsOctober 14, 2025Materials today. Bio

  Tea-derived extracellular vesicles-mediated PDRN delivery activates cAMP-HIF-1α to restore intestinal homeostasis in inflammatory bowel disease

  Cao T, Wan R, Li X, Hu X, Hu C, Liang Y, Deng M, Wang X, Yuan Z, Hu C.
  →
• In the journalsSeptember 25, 2025Experimental and therapeutic medicine

  Thermal-denatured PDRN exhibits increased in vitro pharmacological activities: A functional role of single-stranded DNA random coils

  Lim HW, Huang YH, Baek HS, Kim HG, Kim KE, Lim CJ.
  →
• In the journalsSeptember 1, 2025Journal of pharmacopuncture

  Ultrasound-Guided Pharmacopuncture for Lateral Epicondylitis Initially Misdiagnosed Due to Incomplete Common Extensor Tendon Evaluation: a case report

  Ahn T, Lee D, Moon J, Kim J, So Y, Cho HG, Ji S, Lee S, Oh M, Kim CH.
  →
• In the journalsSeptember 1, 2025Journal of cosmetic dermatology

  Letter to the Editor: Use of Polydeoxyribonucleotide, Retinoic Acid, and Laser in the Treatment of Postinflammatory Hyperpigmentation

  de Oliveira RRC.
  →
• In the journalsAugust 30, 2025Pharmaceutics

  Plasma-Engineered PDRN: Surface Charge Neutralization and Nanosizing Enhance Uptake and Regeneration Potential

  Park SJ, Lee DH, Yoon KB, Kim A, Jung CY, Kim ST, Brito S, Bin BH.
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• In the journalsAugust 23, 2025Bioactive materials

  Biomimetic aligned bacterial cellulose dressing containing polydeoxyribonucleotide for promoting wound healing

  Zhu X, Liu F, Jin T, Chen H, Chung SM, Chen C, Lee IS.
  →
• In the journalsAugust 20, 2025European journal of pharmacology

  Adenosine A<sub>2A</sub> receptor agonist polydeoxyribonucleotide ameliorates acetic acid-induced ulcerative colitis via modulating PI3K/Akt/VEGF signaling pathway

  Lee J, Ko IG, Lee M, Hwang L, Kim SH, Jeon H, Shin HC, Lee S, Park SB, Choi HI, Joo KR, Cha JM, Shin HP, Jeon
  →
• In the journalsAugust 19, 2025International journal of biological macromolecules

  Polydeoxyribonucleotide-spermidine nanoparticles: Preparation, characterization, and verification of skin anti-aging efficacy

  Liu Y, Hu W, Pei X, Zhu J, Meng H, Lyu Y, Qu Z.
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• In the journalsAugust 18, 2025Aesthetic plastic surgery

  Air-Botulinum Neurotoxin and Polydeoxyribonucleotide Injections for Acne Scar Treatment

  Park MH, Hwang SK, Hwang JK, Chua D, Yi KH.
  →
• In the journalsAugust 9, 2025Cureus

  First Reported Use of aiva® Re-Verse, a Novel Combination Injection Protocol for Facial Rejuvenation: A Report of Three Cases

  Chaudhry M.
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• In the journalsAugust 9, 2025npj Biofilms and Microbiomes

  Periodontitis-associated Fusobacterium nucleatum promotes ulcerative colitis by ferroptosis-mediated gut barrier disruption

  A gum-disease bacterium and its effect on colitis, in a mouse model. Not a PDRN paper; listed for the system.
  →
• In the journalsAugust 7, 2025Pharmaceutics

  Comparison of Polynucleotide and Polydeoxyribonucleotide in Dermatology: Molecular Mechanisms and Clinical Perspectives

  Kim ST.
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• In the newsAugust 1, 2025Harvard Health

  A new approach to peripheral artery disease

  A trial in people with diabetes and poor circulation in the legs reports better walking ability on a newer class of medicine, per the source.
  →
• In the journalsJuly 9, 2025Journal of proteome research

  Elucidating Interactome Dynamics of the A2A Adenosine Receptor in the Presence of Polydeoxyribonucleotide

  Lee W, Son A, Ji J, Han E, Cho JY, Kim JW, Kim YO, Kong HJ, Kim H.
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• In the journalsJuly 4, 2025International journal of biological macromolecules

  Injectable in situ-forming silk fibroin-based hydrogel dressing with MXene/polydeoxyribonucleotide for wound protection and regeneration

  Jang J, Chung HR, Lee SM, Lee EJ, Han CM.
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• In the journalsJuly 1, 2025Bioscience, biotechnology, and biochemistry

  PDRN-like marker DNA shows skin beneficial properties through its single-stranded form

  Lim HW, Huang YH, Baek HS, Kim HG, Kim KE, Lim CJ.
  →
• In the journalsJune 13, 2025International journal of molecular sciences

  Comparative Analysis of Melatonin and Polydeoxyribonucleotide: Possible Benefits of Co-Treatment Effects and Potential Synergistic Applicability

  Jang SK, Choi J, Lim HW, Kim HG, Yoo YM.
  →
• In the journalsJune 8, 2025Biochemical and biophysical research communications

  Effects of polydeoxyribonucleotide derived from Gynostemma pentaphyllum callus on skin barrier function

  Kim E, Choi S, Jang J, Shin HY, Ahn K, Kim SJ, Seo HH, Lee JH, Moh SH.
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• In the journalsJune 2, 2025Orthopaedic journal of sports medicine

  Therapeutic Effects of Polydeoxyribonucleotide and Atelocollagen into Achilles Tendon Injury in a Rat Model

  Kim DS, Hui Won Y, Park SH, Seo JH, Ko MH, Kim GW.
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• In the journalsAugust 23, 2016Frontiers in pharmacology

  Adenosine Receptor Stimulation by Polydeoxyribonucleotide Improves Tissue Repair and Symptomology in Experimental Colitis

  Pallio G, Bitto A, Pizzino G, Galfo F, Irrera N, Squadrito F, Squadrito G, Pallio S, Anastasi GP, Cutroneo G,
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• In the journalsJanuary 29, 2010Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA

  Efficacy of intra-articular polynucleotides in the treatment of knee osteoarthritis: a randomized, double-blind clinical trial

  Vanelli R, Costa P, Rossi SM, Benazzo F.
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• In the journalsOctober 1, 2009Cardiovascular & hematological agents in medicinal chemistry

  Polydeoxyribonucleotide (PDRN): a safe approach to induce therapeutic angiogenesis in peripheral artery occlusive disease and in diabetic foot ulcers

  Altavilla D, Bitto A, Polito F, Marini H, Minutoli L, Di Stefano V, Irrera N, Cattarini G, Squadrito F.
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Where the items come from. Journal items include every PubMed-indexed paper with PDRN or polydeoxyribonucleotide in its title or abstract since June 2025, retrieved from Europe PMC, together with a small number of earlier papers cited in our pipeline. Press items are selected by hand from publications that are free to read: BeautyMatter, Cosmetics Business, Experimental and Molecular Medicine, Harvard Health, Healthline, ScienceDaily, Scientific Reports, Tien Phong, npj Biofilms and Microbiomes.

Each item shows its headline, its source and its date, with one line drawn from the source. Nothing is reproduced in full, nothing is backdated, and nothing is presented as Synthena research.